ABSTRACT
Either of electrosurgical laparoscopic ovarian drilling [LOD]or gonadotropin [hMG] therapy is the second choice for induction of ovulation in clomiphene citrate resistance patients with polycystic ovarian disease, this study aim to compare both modalities [LOD and hMG]. Comparative study Bab El-Sharia University Hospital. Seventy five patients with anovulatory infertility due to PCOD were recruited from infertility clinic, the patients subdivided into two groups : first group [40 patients] treated with hMG, and second group [35 patients] subjected to LOD. The results of menstrual pattern, hormonal response, ovulation pattern and occurrence of pregnancy were compared between both modalities of treatment. Improved menstrual pattern 90% versus 70%, ovulation rate 79% versus 75%, pregnancy rate 40% versus 32.5% in LOD and hMG treated groups respectively. The rate of twin pregnancy was 7% in LOD treated group versus 23% in hMG treated group. No abortion occurred with LOD compared with 23% abortion rate in hMG treated group. The outcome of pregnancies in LOD was 100% healthy live birth compared with 76.9% in hMG treated group. NO hyperstimulation associated with LOD. The results with LOD are some what superior to the results with hMG